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Symbol Name ID |
Ncoa3
nuclear receptor coactivator 3 MGI:1276535 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | decreased splenocyte apoptosis |
increased B cell proliferation |
increased T cell proliferation |
enlarged spleen |
abnormal lymphopoiesis |
increased B cell number |
increased CD4-positive, alpha-beta T cell number |
increased CD8-positive, alpha-beta T cell number |
increased lymphocyte cell number |
increased leukocyte cell number |
abnormal B cell morphology |
abnormal spleen red pulp morphology |
increased spleen germinal center size |
increased circulating interleukin-1 beta level |
increased circulating interleukin-6 level |
increased circulating tumor necrosis factor level |
decreased interleukin-1 beta secretion |
increased interleukin-6 secretion |
increased tumor necrosis factor secretion |
increased susceptibility to endotoxin shock |
increased susceptibility to bacterial infection induced morbidity/mortality |
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| Availability | Mouse Genotype | |||||||||||||||||||||
| Ncoa3tm1Jxu/Ncoa3tm1Jxu | ||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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